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한국과학사학회지, 제29권 제2호 (2007), 201-229

이호왕의 유행성출혈열 연구와 한탄바이러스 발견 (Ho Wang Lee's Research of Epidemic Hemorrhagic Fever and Discovery of Hantaan Virus)

by 신미영 (Mi Young Shin)
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초록 This paper argues that Ho Wang Lee's discovery of Hantaan Virus as the agent of Epidemic Hemorrhagic Fever(EHF) was the result of repeated failures and trials on new objects and new experimental methods. Generally speaking, scientific papers describe the research process as going a straight way leading to the final results. However, researches in the real world are full of trial-and-errors, misunderstandings, and complex interactions among elements in the laboratory. Ho Wang Lee's research is a good case to show such characteristics of the scientific research. In this paper, Lee's researches from 1970 to 1980 are examined into three periods. First, from 1970 to 1973, he studied about EHF using wild rats as an experimental object. Wild rats were widely suspected to have the agent of EHF but he failed to get any results. During the second period from 1974 to 1976, he identified an agent of EHF, Korea Antigen, by introducing a new experimental object, the lung of wild rats, and a new method, Fluorescent Antibody Technique. For last 4 years from 1977 to 1980, Lee clarified its physicochemical features. With the results, the Korea Antigen was registered as the agent of EHF, Hantaan Virus in 1980.
주요어 Ho Wang Lee, Hantaan virus, Epidemic Hemorrhagic Fever, Korea Antigen, discovery, experimental object and method, agent, virus, Fluorescent Antibody Technique, lungs

신미영 (Mi Young Shin), "이호왕의 유행성출혈열 연구와 한탄바이러스 발견 (Ho Wang Lee's Research of Epidemic Hemorrhagic Fever and Discovery of Hantaan Virus)", 『한국과학사학회지』 29권 2호 (2007), 201-229


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List of Articles
분류 제목
제29권 제2호 이호왕의 유행성출혈열 연구와 한탄바이러스 발견 (Ho Wang Lee's Research of Epidemic Hemorrhagic Fever and Discovery of Hantaan Virus) file
신미영 (Mi Young Shin)
2007 201-229
제29권 제2호 명대 천문 "사습 (私習)"의 금지령과 천문서적의 출판: 그 이념과 실제 (The Ban on the Private Study of Astrology and Publication of Books on Astrology in Ming Dynasty: Ideas and Reality) file
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2007 231-260
제29권 제2호 유럽의 열대 자연에 대한 식물지리학적 발견 (Europe`s Botanico-Geographical Discovery of the Tropics) file
이종찬 ( Jong Chan Lee )
2007 261-291
제29권 제2호 슈뢰딩거의 "유전자(gene)", 제몬의 "기억(mneme)" (Schrodinger`s Gene and semon`s Mneme) file
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2007 293-315
제29권 제2호 분광학의 공장: 조지 러셀 해리슨의 자동화 기계와 MIT Wavelength Tables (A Factory of Spectroscopy: George R. Harrison`s Automatic Machines and the MIT Wavelength Tables) file
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2007 317-350
제29권 제2호 금속활자 밀랍주조법 주형재료: 유성 탄소의 복원실험 연구 (An Experimental Study for Restoration of Mould Material - Oil Carbon-for Metal Type Wax Casting Method) file
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2007 351-373
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